Tacticell Arena is a 2D top-down shooter centered on tactical squad management with a primary focus on local PvP. The game features shared-screen gameplay where each player controls a squad of three soldiers. At any time, the player directly controls one soldier using the controller, with the ability to switch control between any of the three squad members instantly. The two soldiers not being directly controlled can receive tactical orders to coordinate movements and secure objectives.

The gameplay involves navigating the arena, engaging the opposing player’s units, and collecting power-ups that modify unit statistics. The game includes a variety of adjustable match settings to customize the experience.